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INV501
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DEVELOPING TOMORROW’S CANCER THERAPIES. TODAY.
Corporate profile
Private – spin-out from APEIRON Biologics AG
Launched in January 2022
Highly experienced management team with strong scientific and capital markets expertise
In-house acumen in discovery, development, clinical trials, CMC and finance
Seeking funding through equity investment and or partnering
Investment case: Excellent basis for future value growth
Unencumbered focus on discovery and development of innovative cancer immunotherapies
Proprietary cell-therapy platform enabling out-patient treatment of hard-to-access solid tumors
Individualised, patient-centric approach
Shown to be safe and well-tolerated in clinical trials
Lead candidate expected to enter Phase 2 in 2024
Complementary, high-potential orally available small molecule for tumor-specific immune activation and tumor-cell killing
In-house innovation hub driving long-term pipeline growth
Innovative immuno-oncology pipeline
TARGETS
PROJECTS
EARLY STAGE
CLINICAL
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
Cbl-b
(via platform)
APN401
· Various solid tumors
· PBMCs using siRNA
INV441
· Glioblastoma
· TILs using siRNA
Immune activation
INV501
· Melanoma & glioblastoma
· Small molecule for oral application
Why we target Cbl-b
Modulating Cbl-b is central to fighting tumor cells in a broad range of tumor indications
Cbl-b is involved in several negative regulatory pathways
Cbl-b deficiency activates a variety of immune cells for tumor destruction
For further information, please visit our main website:
HOME
Innovative immuno-oncology pipeline
Targets
Projects
EARLY STAGE
CLINICAL
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
Cbl-b
(via EPIC platform)
APN401
· Various solid tumors
· PBMCs using siRNA
INV441
· Glioblastoma
· TILs using siRNA
Immune activation
INV501
· Various solid tumors
· Small molecule for oral application
Why we target Cbl-b
Modulating Cbl-b is central to fighting tumor cells in a broad range of tumor indications
Cbl-b is involved in several negative regulatory pathways
Cbl-b deficiency activates a variety of immune cells for tumor destruction
For further information, please visit our main website:
HOME